André P Schmidt Selected Research

Guanosine

4/2010	Changes in purines concentration in the cerebrospinal fluid of patients experiencing pain: a case-control study.
2/2010	Guanosine prevents thermal hyperalgesia in a rat model of peripheral mononeuropathy.
2/2009	The NMDA antagonist MK-801 induces hyperalgesia and increases CSF excitatory amino acids in rats: reversal by guanosine.
10/2008	Antinociceptive effects of intracerebroventricular administration of guanine-based purines in mice: evidences for the mechanism of action.
1/2008	Quinolinic acid-induced seizures stimulate glutamate uptake into synaptic vesicles from rat brain: effects prevented by guanine-based purines.
4/2005	In vivo quinolinic acid increases synaptosomal glutamate release in rats: reversal by guanosine.
1/2005	Effects of chronic administered guanosine on behavioral parameters and brain glutamate uptake in rats.
1/2005	Intracerebroventricular guanine-based purines protect against seizures induced by quinolinic acid in mice.
9/2004	Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.
4/2004	Anticonvulsant effect of GMP depends on its conversion to guanosine.

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André P Schmidt Research Topics

Disease

12	Pain (Aches) 01/2022 - 12/2005
8	Seizures (Absence Seizure) 01/2008 - 08/2003
4	Chronic Pain 11/2021 - 02/2009
3	Gout 01/2022 - 11/2021
3	Hyperuricemia 01/2022 - 11/2021
3	Brain Injuries (Brain Injury) 11/2020 - 09/2004
3	Epilepsy (Aura) 01/2008 - 01/2005
2	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2022 - 03/2009
2	Fibromyalgia (Fibrositis) 01/2022 - 11/2021
2	Postoperative Pain 12/2021 - 07/2007
2	Acute Pain 04/2010 - 02/2009
2	Hyperalgesia 02/2010 - 02/2009
1	Cognitive Dysfunction 11/2020
1	Postoperative Cognitive Complications 11/2020
1	Brain Death (Brain Dead) 01/2017
1	Craniocerebral Trauma (Head Injury) 01/2017
1	Labor Pain 11/2015
1	Hypotension (Low Blood Pressure) 06/2010
1	Neuralgia (Stump Neuralgia) 02/2010
1	Body Weight (Weight, Body) 02/2010
1	Mononeuropathies (Mononeuritis Multiplex) 02/2010
1	Ischemia 12/2007
1	Critical Illness (Critically Ill) 06/2006
1	Hypothermia 02/2006
1	Neoplasms (Cancer) 12/2005
1	Mania (Manias) 12/2004
1	Bipolar Disorder (Manic Depressive Psychosis) 12/2004
1	Hypoxia (Hypoxemia) 04/2004
1	Malnutrition (Nutritional Deficiencies) 08/2003
1	Nervous System Diseases (Neurological Disorders) 09/2002

Drug/Important Bio-Agent (IBA)

11	PurinesIBA 01/2022 - 04/2004
10	Glutamic Acid (Glutamate)FDA Link 01/2017 - 08/2003
10	GuanosineIBA 04/2010 - 04/2004
8	GuanineIBA 02/2016 - 04/2004
6	Quinolinic AcidIBA 01/2008 - 08/2003
5	NucleosidesIBA 11/2015 - 09/2004
4	Proteins (Proteins, Gene)FDA Link 11/2020 - 08/2003
4	Adenine FDA LinkGeneric 02/2016 - 10/2008
3	purineIBA 01/2022 - 11/2021
3	EnzymesIBA 01/2022 - 11/2021
3	Xanthine OxidaseIBA 01/2022 - 11/2021
3	Allopurinol (Remid)FDA LinkGeneric 01/2022 - 11/2021
3	Inosine FDA Link 02/2016 - 09/2004
3	Adenosine (Adenocard)FDA LinkGeneric 11/2015 - 04/2004
3	N-Methylaspartate (NMDA)IBA 02/2009 - 01/2005
2	Analgesics (Analgesic Drugs)IBA 01/2022 - 12/2021
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2020
2	Dizocilpine Maleate (Dizocilpine)IBA 02/2009 - 01/2008
2	Guanosine Monophosphate (5' Guanylic Acid)IBA 01/2008 - 04/2004
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2008 - 04/2004
2	Guanosine Diphosphate (GDP)IBA 01/2005 - 09/2004
2	dendrotoxinIBA 01/2005 - 01/2005
1	Phosphopyruvate Hydratase (Enolase)IBA 11/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2017
1	Acetic Acid (Vinegar)FDA LinkGeneric 02/2016
1	Capsaicin (Zostrix)FDA Link 02/2016
1	Inosine Monophosphate (IMP)IBA 04/2010
1	Uric Acid (Urate)IBA 04/2010
1	Pharmaceutical PreparationsIBA 02/2010
1	Starch (Cornstarch)IBA 03/2009
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 03/2009
1	Ringer's LactateIBA 03/2009
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 02/2009
1	Excitatory Amino AcidsIBA 02/2009
1	Morphine (MS Contin)FDA LinkGeneric 02/2009
1	Riluzole FDA LinkGeneric 02/2009
1	Aspartic Acid (Aspartate)FDA Link 02/2009
1	ConvulsantsIBA 01/2008
1	Excitatory Amino Acid AgentsIBA 12/2007
1	Midazolam (Versed)FDA LinkGeneric 07/2007
1	Clonidine (ST 155)FDA LinkGeneric 07/2007
1	Dexmedetomidine FDA Link 07/2007
1	Anesthetics (Anesthetic Agents)IBA 02/2006
1	Opioid Analgesics (Opioids)IBA 12/2005
1	Guanosine Triphosphate (GTP)IBA 01/2005
1	Ouabain (G Strophanthin)IBA 12/2004
1	nucleotidaseIBA 09/2004
1	Pentylenetetrazole (Metrazol)IBA 09/2004
1	triphosphoric acid (triphosphate)IBA 09/2004
1	Dihydrotachysterol (AT 10)IBA 09/2004
1	Adenosine Diphosphate (ADP)IBA 09/2004
1	alpha,beta-methyleneadenosine 5'-diphosphateIBA 04/2004
1	5'-Nucleotidase (5' Nucleotidase)IBA 04/2004
1	ebselenIBA 09/2002

Therapy/Procedure

2	Therapeutics 01/2022 - 11/2021
2	Oral Administration 01/2022 - 11/2021
1	Preanesthetic Medication 12/2021
1	Hysterectomy 12/2021
1	Spinal Anesthesia 06/2010
1	Ligation 02/2010
1	Hemodilution 03/2009
1	Premedication 07/2007
1	Catheters 06/2006